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I want to get healthier. Close Health Alerts from Harvard Medical School Get helpful tips and guidance for everything from fighting inflammation to finding the best diets for weight loss Close Stay on top of latest health news from Harvard Medical School. Sign me up. Take the lowest dose first, and then raise it only if it doesn't work. Many people obtain acceptable relief of their symptoms, such as pain and swelling, at low to moderate doses.
Stop as soon as you can. Severe pain demands a response, but when it becomes a dull ache, try to ease off the NSAIDs and shift to comforting remedies like hot baths or cold packs. For pain relief, try acetaminophen Tylenol, other brands first. Ask your pharmacist or doctor if you're not sure. UK website. Tablets or capsules should normally be swallowed whole and without chewing with water or food to stop them upsetting your stomach. It's usually safe to drink alcohol while taking NSAIDs, but drinking alcohol excessively may irritate your stomach.
This is known as taking an overdose. Contact your GP or NHS for advice immediately if you take too much of your medicine and you experience problems such as feeling or being sick, an upset stomach or drowsiness.
Call for an ambulance immediately if you or someone else experiences serious effects of an overdose, such as fits seizures , breathing difficulties, or loss of consciousness. The main alternative for pain relief is paracetamol , which is available over the counter and is safe for most people to take. Front Physiol. Goldstein JL, Cryer B. Gastrointestinal injury associated with NSAID use: a case study and review of risk factors and preventative strategies.
Drug Healthc Patient Saf. Non-steroidal anti-inflammatory drugs: An overview of cardiovascular risks. Pharmaceuticals Basel. Ther Clin Risk Manag. Nonsteroidal Anti-Inflammatory Drugs and the Kidney. Schiff M, Minic M. Comparison of the analgesic efficacy and safety of nonprescription doses of naproxen sodium and Ibuprofen in the treatment of osteoarthritis of the knee. J Rheumatol. Your Privacy Rights. To change or withdraw your consent choices for VerywellHealth.
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Always check with your doctor if bruising is a problem for you. Interaction with Other Medicines NSAIDs can increase or decrease the actions of other medicines you take including high blood pressure medicines, blood thinners and antidepressants. They can also interact with alcohol.
Additionally, because NSAIDs can be found in many OTC products including allergy, sleep, cough and cold medicines it is easy to accidentally take more than what is recommended. Always check for interactions with your doctor or pharmacist before adding any drug or dietary supplement to your existing treatment plan. Side effects are more likely to happen if you take high doses of NSAIDs or if you have taken them for a long time.
Some side effects are mild and go away on their own, but others are more serious and need medical attention. More serious stomach problems include ulcers and bleeding in the GI tract. Call your doctor right away if you have severe abdominal pain; a black, tarry bowel movement; or see any blood in your stool. Solutions: Stomach discomfort caused by NSAID use can usually be avoided by taking each dose after a full meal or with an antacid or other drug that protects the stomach.
It increases your risk of internal bleeding. Be careful of combining medicines. Cardiovascular Problems All NSAIDs other than aspirin increase your chances of developing high blood pressure or having a heart attack or a stroke. People who already have cardiovascular disease are at the greatest risk. Smoking, high blood pressure, high cholesterol and diabetes are significant risk factors for heart disease.
Commit yourself to controlling, reducing or eliminating those other risk factors. If you take medicine for high blood pressure, have your pressure checked regularly while taking NSAIDs. If you take low-dose aspirin to prevent heart attack and stroke, some NSAIDs, including ibuprofen and naproxen, can interfere with that protective effect. Solutions: Be aware of allergic symptoms, like rash, hives, facial swelling, wheezing and difficulty breathing.
If you have a mild reaction, antihistamines like diphenhydramine Benadryl will ease the symptoms until the medicine works its way out of your system.
If you have a serious reaction, like throat swelling or breathing difficulty, call immediately. Solutions: If you know you have kidney disease, check with your doctor before you take any NSAID, including over-the-counter ones.
Simple blood and urine tests can be used to test your kidney function. NSAID-related kidney problems are usually reversible once you stop taking these medicines. Certain herbal supplements, including willow bark, are also known to thin the blood or prevent clotting, so you must be careful about taking them together with NSAIDs.
Because of their effects on blood clotting, your doctor will tell you to stop taking NSAIDs before any surgery.
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